Give Back Health Clinic Collection Mood-D® delivers clinically proven doses of acetyl-L-carnitine and affron® saffron in a powerful formula that enhances mood, reduces stress and restores mental balance. This synergistic combination provides adolescents and adults with fast-acting, long-lasting support for emotional stability, enhanced cognition and complete mental wellbeing. It is a listed medicine (AUST L 483951) on the Australian Register of Therapeutic Goods (ARTG).

• Promotes healthy mood and mental wellbeing.
• Reduces the occurance and severity of poor mood status (anxiety and depression).
• Supports mental health stability, including reducing and relieving symptoms of stress and anxiety.
• Clinical trials have demonstrated saffron (affron®) and acetyl-L-carnitine are as effective as commonly prescribed SSRIs.
• Aids neurotransmitter synthesis and healthy brain chemistry.
• Promotes mental wellbeing during times of increased demand.
• Supports healthy cognitive, mental and nervous system function.
• Clincally dosed inline with the literature for maximum therapeutic impact.
• Targeted, fast acting, clinic-grade mood support.
• Combines two highly researched ingredients, acetyl-L-carnitine and affron® saffron, both clinically proven as effective options for mood support.
• Contains ingredients that can complement antidepressant medications and have shown comparable effectiveness in clinical research, with up to 79% fewer side effects.

• Clinical trials have demonstrated affron® saffron and acetyl-L-carnitine are as effective as commonly prescribed SSRIs.
  Helps regulate fatty acid transport across the inner membrane of mitochondria.
  ALC crosses the blood brain barrier to provide more pronounced antidepressant effects.
  ALC has numerous functions relevant to mental health, such as facilitating the uptake of acetyl CoA into the mitochondria during fatty acid oxidation, enhancing acetylcholine production, stimulating protein and membrane phospholipid synthesis, and preventing excessive neuronal cell death.
• Helps modulate neurotransmitters (e.g. serotonin, dopamine)
• Provides neuroplasticity effects in cerebral regions that are at the basis of depression and helps modulate neurotransmitters involved in depression.
• Increases BDNF levels.
• Provides antioxidant effects.
• Provides anti-inflammatory effects.
• Provides serotoninergic effects.
• Provides HPA modulating effects.
• Provides neuroprotective effects.

See factsheet for specific scientific findings and a full list of references.

• Significantly reduces depressive symptoms in adolescents and adults.
• Significantly improves mood and reduces stress and anxiety.
• Suitable for use alongside antidepressants.
• Shown to be as effective as antidepressants.
• Significantly improves sleep quality and mood upon waking.
• Improves psychological symptoms in women experiencing perimenopause.
• Provides antioxidant effects.
• Provides anti-inflammatory effects.
• Provides serotoninergic effects.
• Provides hypothalamus-pituitary adrenal (HPA) modulating effects.
• Provides neuroprotective effects.
• Shown to be as effective as antidepressants with 79% fewer side effects.
• Helps regulate fatty acid transport across the mitochondria inner membrane.
• Crosses the blood brain barrier for effective antidepressant effects.
• Facilitates the uptake of acetyl CoA into the mitochondria during fatty acid oxidation.
• Enhances acetylcholine production.
• Stimulates protein and membrane phospholipid synthesis.
• Helps prevent excessive neuronal cell death.
• Provides neuroplasticity effects in the hippocampus.
• Increases BDNF levels.
• Increases the up-regulation of mGLU2 receptors in the brain.
• Helps modulate neurotransmitters (e.g serotonin, dopamine).
• Reduces pain.

• Adolescents, adults and older individuals seeking to support mood, cognition and mental wellbeing.
• People with stress, anxiety, depression or low mood.
• People on pharmaceutical medication or those trying to avoid or eliminate use.
• People looking to maintain healthy emotional balance during times of stress.
• People with chronic pain and underlying mental health disturbances.
• Individuals seeking support for focus, energy production and nervous system health.
• Those who prefer a non-pharmaceutical and evidence-based approach to mood and wellbeing.
• Health-conscious individuals wanting to support neurotransmitter synthesis and brain health.

• To reduce the occurrence and severity of poor mood status (anxiety and depression).
• To promote healthy mood and mental wellbeing.
• To support mental health stability, including reducing and relieving symptoms of stress and anxiety.
• To assist neurotransmitter synthesis and healthy brain chemistry.
• To promote mental wellbeing during times of increased demand.
• To support healthy cognitive, mental and nervous system function.

When selecting a mood support product, key factors include interactions, ingredient form, clinical dosing, purity, clinical research, excipient profile and manufacturing standards. This practitioner-only formulation stands apart through its clinical integrity and evidence-aligned design. Key points of difference include:

• Therapeutic dosing based on the latest research.
Mood-D® contains the clinically trialled daily dosage of affron® saffron (28 mg) and acetyl-L-carnitine (2 g).
• Bioavailable and researched ingredient forms to maximise absorption and clinical outcomes.
We used affron® saffron as it's the most studied, standardised saffron extract.
• Manufactured in a TGA-licensed GMP facility to ensure consistent quality.

• Comprehensive third-party testing for potency, purity and contaminants.

• Minimal excipients, no unnecessary fillers or additives. Mood-D® is clean formula with only the necessary excipients added as a requirement of the manufacturing process. Even our capsules are the cleanest avialble, made from water and hypromellose derived from sustainably sourced pine trees.

This product is designed to offer clinicians peace of mind and patients better outcomes, supporting targeted use in a range of clinical applications.

No major interactions.

At Give Back Health, we follow a conservative risk/benefit approach and recommend healthcare practitioners assess use on a case-by-case basis, depending on individual patient needs, context and response to treatment.

• Saffron: when used orally in amounts exceeding those commonly found in foods, larger amounts of saffron have uterine stimulant and abortifacient effects. Recommend avoid use.
• Acetyl-L-carnitine: While Acetyl-L-carnitine is not specifically contraindicated in pregnancy and lactation, there is insufficient reliable evidence so we recommend avoid use.

Take 2 capsules twice a day. Although both ingredients can help with sleep, some people can feel stimulated from ALC, so it may be more suitable to recommend patients take 2 capsules in the morning and 2 at lunchtime.

• For mood support, the clinically trialled daily dosage for affron® saffron is 28 mg.
• For mood support, the clinically trialled daily dosage for acetyl-L-carnitine is 2 g.

Give Back Health Clinic Collection Mood-D® provides the clinically trialled dosage of both ingredients.

Results are generally seen within 2-4 weeks, with further improvement by 6-12 weeks.

Give Back Health Clinic Collection Mood-D® is a clean formula free from many commonly used excipients, making it a suitable option for many. It is an ultra-low excipient formulation with minimal low-to-no allergen excipients. See the Free Froms & Allergy Info details in the main product description above.

Give Back Health Clinic Collection Mood-D® is manufactured and tested in TGA-registered GMP facilities here in Australia, ensuring high standards of quality, safety and efficacy. Every product, every batch, with no exceptions.

• We use affron® saffron, DNA certified, 100% vertically integrated and clinically trialled saffron sourced from Spain.
• We use gold-standard Capsugel® Vcaps® capsules from Lonza, widely considered the cleanest on the market. Unlike many capsules that contain gelatine or unnecessary additives like sodium lauryl sulphate, ours are made from just two ingredients: plant-based hydroxypropylmethylcellulose (HPMC) (AKA hypromellose), derived from sustainably sourced pine trees, and water. That’s it. These capsules are vegan, non-GMO Project Verified, Kosher and Halal certified, and Vegetarian Society approved.

Give Back Health Clinic Collection Mood-D® is most commonly used alongside our MagRegulate®, MagRelax®, L-Theanine, Curcuma Phospholipids, 5-HTP, NAC, RejuveGen® and Zinc Picolinate for additional support, depending on clinical goals.