Give Back Health Zinc Picolinate is a practitioner-only nutritional supplement that provides 100% pure medicine-grade zinc picolinate. It comes in powder form and is designed for extemporaneous compounding and prescribing under practitioner supervision. Zinc picolinate is a perfect first line option for zinc supplementation. It has a demonstrated high bioavailability for optimal utilisation of zinc in the body and has a strong history of use in the mental health space (but can be used anywhere zinc is indicated).

• Zinc picolinate shows a high degree of promise in mental health, reproductive health, metabolic syndromes and immune function.

• A good quality, methodologically sound double-blind placebo controlled cross-over clinical trial demonstrated that zinc picolinate is significantly better absorbed than zinc citrate or zinc gluconate in healthy adults.
• Zinc is critical to brain-derived neurotropic factor (BDNF), which promotes neurogenesis and neuroplasticity; vital to maintaining cognitive funciton.
• Provides antioxidant effects.
• Zinc modulates NMDA receptor activation sensitivity.
• Zinc is integral to nervous system development, maintenance and normal function.
• Zinc is associated with emotional balance. It is maintained at high levels within glutamatergic neurons in the limbic system, acting as an inhibitory modulator.
• Zinc absorption is impacted by ageing, impaired gastrointestinal function and by commonly used medications (oral hypoglycaemics, antacids, anti-inflammatories and others).
• A meta-analysis confirmed that serum zinc levels are lower in people with symptoms of depression compared to healthy controls.

See factsheet for additional and specific scientific findings, including a full list of references.

• Immediately available for metabolic processes.
• A good quality, methodologically sound double-blind placebo controlled cross-over clinical trial demonstrated that zinc picolinate is significantly better absorbed than zinc citrate or zinc gluconate in healthy adults.
• Zinc is critical to brain-derived neurotropic factor (BDNF), which promotes neurogenesis and neuroplasticity; vital to maintaining cognitive funciton.
• Provides antioxidant effects.
• Zinc modulates NMDA receptor activation sensitivity.
• Zinc is integral to nervous system development, maintenance and normal function.
• Zinc is associated with emotional balance. It is maintained at high levels within glutamatergic neurons in the limbic system, acting as an inhibitory modulator.
• Zinc absorption is impacted by ageing, impaired gastrointestinal function and by commonly used medications (oral hypoglycaemics, antacids, anti-inflammatories and others).
• A meta-analysis confirmed that serum zinc levels are lower in people with symptoms of depression compared to healthy controls.

• People with acute viral infection.
• People with mental health presentations.
• People with metabolic syndromes (e.g. T2DM, NAFLD).
• Children and adolescents.
• Women seeking support for reproductive health.
• Male and females during preconception care.
• People seeking healthy ageing.

• The first option in any treatment program involving zinc due to rapid absorption and utilisation in the body.
  Fast response to:
  - acute viral infection,
  - mental health presentation.
• For growth and development in children and adolescents.
• For metabolic syndromes (e.g. T2DM, NAFLD).
• For reproductive health and preconception care (male and female).
• Healthy ageing.
• For mental health support.
• Zinc is integral to nervous system development, maintenance and normal function.
• Zinc is associated with emotional balance. It is maintained at high levels within glutamatergic neurons in the limbic system, acting as an inhibitory modulator.
• Zinc absorption is impacted by ageing, impaired gastrointestinal function and by commonly used medications (oral hypoglycaemics, antacids, anti-inflammatories and others).
• A meta-analysis confirmed that serum zinc levels are lower in people with symptoms of depression compared to healthy controls.

When selecting a zinc picolinate product, key factors include clinical research on the raw material, clinical dosing, purity, excipient profile and manufacturing standards. Unlike herbal ingredients, which are complex and vary significantly across the many different grades available, single nutrients are far simpler to assess. Source and quality are still essential, but they are much easier to control and verify. If a material is authenticated and genuinely pure, the body can be expected to respond the same way regardless of supplier or brand name. Where this cannot be confirmed, the supplier and manufacturing process become critical.

The key questions to ask are: Is it pure? Has every batch been independently tested to confirm this? Is it free from impurities? Is it the correct isomer, where relevant? Is it stable over time and in combination with other ingredients?

Our zinc picolinate meets every one of these criteria. It is authenticated, independently tested on every batch, free from impurities, the correct isomer where relevant, and stable, so you can be confident you are receiving the full clinical dose stated on the label.

This product has been specifically developed for practitioner use and compounding, with:



• High-quality, verified raw materials with full traceability.

• Manufacturing in a TGA-licensed GMP facility in Australia.

• Rigorous third-party testing to ensure potency, purity and absence of contaminants.

• 100% pure zinc picolinate powder with no excipients suitable for sensitive patients and custom blends.

In short, yes. Powders for extemporaneous compounding sit in a unique therapeutic category with its own set of rules. When you choose to use a compounding powder, the expectation is that you will be combining this with other therapeutic nutrients and ingredients to create a personalised medicine. Single ingredient prescribing is, however, possible with extemporaneous compounding ingredients with best practice to ensure that the amount of product in the jar represents the full course for the patient. The quantity of any ingredient you use will be calculated in relation to the prescription length and daily required dose, which is completely specific to an individual patient’s presentation and needs.

• High doses can cause nausea which is more common on an empty stomach.

Yes at a suitable dosage.

• Recommended daily dose is 50 mg – 250 mg (equiv. zinc 10 mg – 50 mg).
• Without knowing your patient’s presentation and requirements, we cannot provide guidelines around appropriate daily dosing and suggest you refer to the literature and common dosage ranges when creating your prescription. Our team of naturopaths are also available for further guidance.

Results are generally seen within 2-6 weeks, with further improvement by 8-12 weeks.

This product contains no excipients. It is 100% pure zinc picolinate.

Give Back Health Clinic Collection Zinc Picolinate is manufactured and tested in TGA-registered GMP facilities here in Australia, ensuring high standards of quality, safety and efficacy. Every product, every batch, with no exceptions. This means the included ingredients are what they claim to be and the products are therefore more likely to have an actual therapeutic impact. This process also prevents counterfeit and adulterated materials from entering the market. While it adds significantly to our costs, we believe this level of integrity should be the industry standard. Please note that we absorb the extra expense ourselves; it is not passed on to you.

Give Back Health Clinic Collection Zinc Picolinate is most commonly used alongside our L-Theanine, Nicotinamide Riboside (NR), NAC, Saffron + Zinc, RejuveGen® and L-Glycine for additional support, depending on clinical goals.

Absolutely. This can be mixed with any other powder product in the Give Back Health Clinic Collection. For further info on compounding personalised medicines for your patients, see our compounding resources, including a compounding calculator, videos and sample recipes based on real-life cases. Alternatively, reach out if you need assistance or guidance with compounding.