Give Back Health Clinic Collection L-Theanine is a practitioner-only nutritional supplement that provides a bio fermented 100% pure medicine-grade L-theanine. It comes in powder form and is designed for extemporaneous compounding and prescribing under practitioner supervision. L-Theanine is a major nonprotein amino acid. It has a fast onset and provides exceptional value in helping promote a relaxed alert state (reducing overwhelm so you can focus) and winding down the mind to block out the noise. L-Theanine shows a high degree of promise in patients experiencing high cortisol on waking. It is also extremely valuable for anticipatory anxiety, sleep disturbances and stress.

• Promotes a relaxed alert state.
• Reduces overwhelm to enable focus.
• Reduces high-cortisol induced excitation on waking.
• Supports sleep onset and disturbances.
• Acts rapidly (within 30 mins) to inhibit excitation.
• Suitable for use both during the day and prior to sleep.

L-theanine crosses the blood-brain barrier and is chemically similar to glutamate. It modulates glutamatergic neurotransmission, may inhibit glutamine binding to glutamate receptors and has been shown to increase GABA, dopamine and serotonin levels. These actions support its calming and focus-enhancing effects.

• Theanine crosses the blood-brain barrier.
• Chemically similar to glutamate, theanine affects glutamatergic neurotransmission and the NMDA receptors.
• Theanine may inhibit glutamine binding to glutamate receptors. It has been shown to increase GABA, serotonin and dopamine levels, which likely contributes to stress reduction.
• Attenuates stress-induced cortisol elevation and sympathetic nervous system activity. 
• Increases alpha wave generation resulting in relaxed alertness and focused attention. 

See factsheet for specific scientific findings and a full list of references.

•  Reduces stress that impacts learning, concentration and comprehension.
• Modulates attention systems.
• Calms the mind / slows down the mind / relaxes the body.
• Helps you fall asleep faster and stay asleep for longer.
• Theanine reduces biomarkers of nervous system excitation.
• Increases alpha wave generation resulting in relaxed alertness and focused attention. 

• People with multiple responsibilities needing calm focus.
• Students (prior to exams or to help focus).
• Anticipatory anxiety.
• High pressure situations.
• People waking with a large cortisol spike.
• People having difficulty falling asleep and staying asleep.
• Those feeling overwhelmed.
• Individuals struggling to quieten the mind and relax into sleep.
• People (including children) with ADHD.
• People with stress, anxiety, concentration and focus challenges. 

• When trying to focus and maintain attention.
• When overwhelmed and unsure where or how to start.
• When ordinary stress is impacting focus and concentration. 
• When ordinary stress is impacting sleep onset and quality.
• When sleep is interrupted by anxious thoughts (high cortisol on waking).
• Before major events.
• When sleep onset is compromised or high cortisol on waking. 

When selecting an L-Theanine product, key factors include clinical research on the raw material, clinical dosing, purity, excipient profile and manufacturing standards. Unlike herbal ingredients, which are complex and vary significantly across the many different grades available, single nutrients are far simpler to assess. Source and quality are still essential, but they are much easier to control and verify. If a material is authenticated and genuinely pure, the body can be expected to respond the same way regardless of supplier or brand name. Where this cannot be confirmed, the supplier and manufacturing process become critical.
The key questions to ask are: Is it pure? Has every batch been independently tested to confirm this? Is it free from impurities? Is it the correct isomer, where relevant? Is it stable over time and in combination with other ingredients?

Our bio-fermented L-theanine meets every one of these criteria. It is authenticated, independently tested on every batch, free from impurities, the correct L-isomer and stable. Branded L-theanine materials can cost up to eight times more, with the price often justified by small, brand-specific clinical trials. Pure L-theanine is the same molecule regardless of its brand name, and it will have the same effect at the same clinical dose. As such, we see no reason for our practitioners to pay eight times more for a name, and choose our high quality, bio-fermented L-theanine instead.

This product has been specifically developed for practitioner use and compounding, with:


• High-quality, verified raw materials with full traceability.

• Manufacturing in a TGA-licensed GMP facility in Australia.

• Rigorous third-party testing to ensure potency, purity and absence of contaminants.

• 100% pure L-theanine powder with no excipients suitable for sensitive patients and custom blends.

This product prioritises efficacy, quality assurance and suitability for tailored prescribing, giving you clinical confidence and patient clarity. Unlike most therapeutic and extemporaneous compounding powders in the marketplace, all our products – including Give Back Health Clinic Collection L-Theanine – are manufactured and tested in TGA-registered GMP facilities here in Australia, ensuring high standards of quality, safety and efficacy. Every product, every batch, with no exceptions. This means the included ingredients are what they claim to be and the products are therefore more likely to have an actual therapeutic impact. This process also prevents counterfeit and adulterated materials from entering the market. While it adds significantly to our costs, we believe this level of integrity should be the industry standard. Please note that we absorb the extra expense ourselves; it is not passed on to you.

We use a premium quality, bio fermented, vegan form of L-theanine.

In short, yes. Powders for extemporaneous compounding sit in a unique therapeutic category with its own set of rules. When you choose to use a compounding powder, the expectation is that you will be combining this with other therapeutic nutrients and ingredients to create a personalised medicine. Single ingredient prescribing is, however, possible with extemporaneous compounding ingredients with best practice to ensure that the amount of product in the jar represents the full course for the patient. The quantity of any ingredient you use will be calculated in relation to the prescription length and daily required dose, which is completely specific to an individual patient’s presentation and needs. 

• L-theanine is generally well tolerated. 
• Antihypertensive drugs: L-theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.

While L-Theanine is not specifically contraindicated in pregnancy and lactation, there is insufficient reliable evidence so we recommend avoid use. Use a risk/benefit approach during pregnancy and lactation due to insufficient safety data.

• We typically recommend sprinkling into water, stirring fairly vigorously and then leaving for a minute to let it fully dissolve. This more often than not ensures it quickly dissolves into water.
• The common range for theanine is 100 mg – 400 mg per day. It is well tolerated at these levels.
• Without knowing your patient’s presentation and requirements, we cannot provide guidelines around appropriate daily dosing and suggest you refer to the literature and common dosage ranges when creating your prescription. Our team of naturopaths are also available for further guidance.

Theanine has a very quick onset. Individuals should experience its effects within 30 minutes, with further improvement by 2-8 weeks.  

This product contains no excipients. It is 100% pure L-theanine powder.

Give Back Health Clinic Collection L-Theanine is manufactured and tested in TGA-registered GMP facilities here in Australia, ensuring high standards of quality, safety and efficacy. Every product, every batch, with no exceptions. This means the included ingredients are what they claim to be and the products are therefore more likely to have an actual therapeutic impact. This process also prevents counterfeit and adulterated materials from entering the market. While it adds significantly to our costs, we believe this level of integrity should be the industry standard. Please note that we absorb the extra expense ourselves; it is not passed on to you.

Give Back Health Clinic Collection L-Theanine is most commonly used alongside our NAC, L-Glycine, Nicotinamide Riboside (NR), Saffron + Zinc, MagRelax® and Sleepatonin® for additional support, depending on clinical goals.

Absolutely. This can be mixed with any other powder product in the Give Back Health Clinic Collection. For further info on compounding personalised medicines for your patients, see our compounding resources, including a compounding calculator, videos and sample recipes based on real-life cases. Alternatively, reach out if you need assistance or guidance with compounding.

Emerging literature supports its use for stress, cognition and neuroprotection. A suggested starting dose is 200 - 400 mg per day, adjusted as needed. Clinical discretion advised.

We’ve updated the scoop to a deeper, narrower design for more accurate dosing. It still measures 200 mg per level scoop. Some older batches had a 50 mg scoop (check the label or batch code if unsure as it is clearly identified on the left panel of the label).

Currently there are trademark restrictions around L-theanine which means it is exceedingly expensive in capsule form. As a powder form, Give Back Health Clinic Collection L-Theanine offers incredible value for money. We do understand that some practitioners may want to create their own capsules, in which case a size 0 or 00 capsule is generally suitable for 200 mg of L-theanine. If you're aiming for 100 mg doses, you may prefer a size 1. Always use a micro-scale or measured scoop for accuracy.