Give Back Health Clinic Collection NMN is a practitioner-only nutritional supplement that provides authenticated, vegan and 100% pure medicine-grade NMN. it comes in powder form and is designed for extemporaneous compounding and prescribing under practitioner supervision. Nicotinamide mononucleotide (NMN) is a popular and researched NAD+ precursor. It provides the body with NAD+, which can be used in an extensive range of metabolic processes.This is the same NMN used in human clinical trials.

• Beta-nicotinamide mononucleotide is the main form of NMN and is commonly referred to as NMN.
• Independent third-party testing results are a must with NMN due to a high risk of adulterated and low purity materials currently being sold in the marketplace.
• NMN is currently not approved for use in Australia. It can, however, be prescribed by healthcare practitioners to their patients as an extemporaneous compounding ingredient following a consultation.

• NMN increases NAD+ levels to prevent, delay, or improve NAD+ dependent aging mechanisms, thereby helping to prevent, delay, or improve the seven diseases of aging. Increases are dose dependant (the more you take the more NAD+ increases, with studies commonly at 250 mg - 1200 mg for best results).
• NMN shows a high degree of promise in healthy ageing, energy optimisation, physical fitness/performance and metabolic health.

Metabolic Health

• NMN increases skeletal muscle insulin signalling, insulin sensitivity, and muscle remodelling in postmenopausal women with prediabetes who are overweight or obese.
• The improvement in muscle insulin sensitivity were reported in a high quality clinical trial as clinically relevant and similar to improvements observed after ~10% weight loss and after 12 weeks of treatment with the insulin sensitizing agent troglitazone in people with obesity.
• Increases insulin stimulated mTOR phosphorylation and gene expression.
• Elevates levels of NAD+ in circulating peripheral blood mononuclear cells (PBMCs).
• Increases NAD+ metabolites when supplemented with NMN.
• Increases NAD+ for use in NAD+ dependent metabolic pathways.
• Becoming overweight or obese is associated with declining levels of NAD+.
• Metabolic disorders (including obesity and T2DM) are associated with a reduced expression of the NAD+ dependent enzymes SIRT1 and 2 due to insufficient quantities of NAD+.
• Provides clinically relevant increases in skeletal muscle insulin sensitivity.
• Upregulation of NAD+ synthesis can influence metabolic processes regulated by sirtuins.

Energy Optimisation

• Upregulates NAD+ for use in NAD+ dependent pathways.
• Increases NAD+ levels, a coenzyme critical to multiple energy and metabolic pathways.
• Detoxification has a high energy requirement.
• NMN is an effective NAD+ precursor, which promotes ATP. Liver detoxification pathways have a high energy requirement.
• The reduced form of NAD+, NADPH, is essential for the biosynthesis of several major antioxidants, including glutathione.
• Increasing NAD+ levels in skeletal muscle can improve energy capacity and endurance.
• Supplementation has been shown to improve aerobic capacity and result in enhanced oxygen uptake (VO2), maximum oxygen uptake (VO2max) and power.

Healthy Ageing

• NMN increases NAD+ levels to prevent, delay, or improve NAD+ dependent aging mechanisms, thereby helping to prevent, delay, or improve the seven diseases of aging.
• NMN shown to maintain biological age on the Insilico 3.0 model (19 blood test parameters), while the placebo group biological age increased significantly during the 60-day trial.
• Increases NAD+ levels in the blood and tissue even in old age.
• Provides NAD+ for the NAD+ dependant mechanisms of ageing (metabolic dysfunction, inflammation, senescence, neurodegeneration).
• Improves validated measures of physical and motor fitness tests in ageing adults, including gait speed and grip strength.
• The cellular bioavailability of NAD+ and related metabolites declines in humans during normal ageing. This reduces the activity of NAD+ dependent sirtuins which play a critical role in genomic stability and energy metabolism.
• Ageing is accompanied by a gradual decline in NAD+ concentration across multiple tissues, including skin, blood, liver, muscles and brain.
• Measures of frailty in older adults shown to improve with NMN supplementation.
• Skeletal muscle tissue is particularly sensitive to NMN. Maintaining muscle tissue is critical to healthy ageing.
• Neurodegeneration is linked to a decline in NAD+ concentrations in the brain.

• People with pre-diabetes.
• People overweight or obese.
• People with metabolic syndrome.
• People with insulin dysregulation or insulin resistance.
• People seeking more energy/improvements in mitochondrial health.
• Chronic health conditions resulting in fatigue.
• Autoimmune diseases with associated fatigue.
• People wanting to prevent, delay or improve chronic illness and diseases of ageing.
• People wanting to support optimal health span.
• People wanting to support memory and nervous system function and reduce the impacts of cognitive decline and neurodegeneration.
• Suitable for adults and older adults.

• To combat normal age related decline in NAD+ synthesis.
• To improve metabolic health and function.
• To improve metabolism of glucose.
• To improve issues with insulin resistance.
• To improve non-specific energy decline.
• As part of detoxification programs.
• As an adjunct to treatment in people with chronic conditions, including autoimmune conditions.
• To improve endurance and lactate tolerance when used in conjunction with exercise.
• To prevent, delay or improve chronic illness and diseases of ageing.
• To improve health span.
• To promote healthy ageing and optimal nervous system health.
• To provide NAD+, which naturally declines with age.
• To promote energy, muscle strength and slow the onset of muscle wasting/sarcopenia.

When selecting an NMN product, key factors include ingredient form, clinical dosing, purity, excipient profile and manufacturing standards. This product has been specifically developed for practitioner use and compounding, with:


• High-quality, verified raw materials with full traceability.
 This is 100% pure NMN powder for personalised dosing or compounding.
• Manufacturing in a TGA-licensed GMP facility in Australia.

• Rigorous third-party testing to ensure potency, purity and absence of contaminants.
This is particularly relevant in the NAD+ market where we have seen results of products claiming to be NR or NMN that show only minimal amounts of the active (or in some cases, a completely different ingredient overall).

In short, yes. Powders for extemporaneous compounding sit in a unique therapeutic category with its own set of rules. When you choose to use a compounding powder, the expectation is that you will be combining this with other therapeutic nutrients and ingredients to create a personalised medicine. Single ingredient prescribing is, however, possible with extemporaneous compounding ingredients with best practice to ensure that the amount of product in the jar represents the full course for the patient. The quantity of any ingredient you use will be calculated in relation to the prescription length and daily required dose, which is completely specific to an individual patient’s presentation and needs.

None to note. NMN is well tolerated in clinical trials.

The NMN has a very slight NMN characteristic flavour profile, but it’s very mild and benign. This is one reason why some people might choose NMN over NR when looking for an NAD+ precursor (as NR has a characteristic chloride profile). Both ingredients increase NAD+ and many people take them both together for a more sustained effect.

Results are generally seen within 1-2 weeks, with further improvement by 10-12 weeks.

This is a clean formula with 100% pure and authenticated NMN powder.

Give Back Health Clinic Collection NMN is manufactured and tested in TGA-registered GMP facilities here in Australia, ensuring high standards of quality, safety and efficacy. Every product, every batch, with no exceptions. This means the included ingredients are what they claim to be and the products are therefore more likely to have an actual therapeutic impact. This process also prevents counterfeit and adulterated materials from entering the market. While it adds significantly to our costs, we believe this level of integrity should be the industry standard. This is particularly relevant in the NAD+ market where we have seen results of products claiming to be NR or NMN that show only minimal amounts of the active (or in some cases, a completely different ingredient overall). Please note that we absorb the extra expense ourselves; it is not passed on to you.

The NMN we use is approved for use as an extemporaneous compounding powder. It is authenticated, vegan, independantly third party tested and 100% pure medicine-grade NMN.

Give Back Health Clinic Collection NMN is most commonly used alongside our NAC, MagRelax®, L-Glycine, L-Theanine, Saffron + Zinc, Natural Energy and Sleepatonin® for additional support, depending on clinical goals.

Absolutely. This can be mixed with any other powder product in the Give Back Health Clinic Collection. For further info on compounding personalised medicines for your patients, see our compounding resources, including a compounding calculator, videos and sample recipes based on real-life cases. Alternatively, reach out if you need assistance or guidance with compounding.

Nicotinamide adenine dinucleotide (NAD+) is an essential molecule that plays a critical role in almost every metabolic process in the body. Through its roles as a cofactor, electron donor and signalling molecule, NAD+ is essential for many biological processes. These include ATP synthesis, DNA repair, secondary messenger signalling, epigenetic regulation of gene expression and cell survival. NAD+ naturally declines with age. The gradual decline of NAD+ concentrations takes place across multiple human organs and tissues, including skin, blood, liver, muscles and brain. Reduced concentration of NAD+ results in suboptimal functioning of the NAD+ dependent pathways. This in turn results in an increase in issues relating to metabolic function, inflammation, senescence and degeneration of the nervous system. When NAD+ dependent mechanism are compromised, diseases of ageing are then more likely to occur. By increasing NAD+ and therefore increasing the activity of the NAD-dependent processes, we can help prevent, delay or improve the NAD+ mechanisms of ageing. In doing so, we can prevent, delay or improve the seven diseases of ageing.

See the NMN factsheet for further information.

Nicotinamide adenine dinucleotide (NAD+) is an essential molecule that plays a critical role in almost every metabolic process in the body. Through its roles as a cofactor, electron donor and signalling molecule, NAD+ is essential for many biological processes. These include ATP synthesis, DNA repair, secondary messenger signalling, epigenetic regulation of gene expression and cell survival. NAD+ naturally declines with age. The gradual decline of NAD+ concentrations takes place across multiple human organs and tissues, including skin, blood, liver, muscles and brain. Reduced concentration of NAD+ results in suboptimal functioning of the NAD+ dependent pathways. This in turn results in an increase in issues relating to metabolic function, inflammation, senescence and degeneration of the nervous system. When NAD+ dependent mechanism are compromised, diseases of ageing are then more likely to occur. By increasing NAD+ and therefore increasing the activity of the NAD-dependent processes, we can help prevent, delay or improve the NAD+ mechanisms of ageing. In doing so, we can prevent, delay or improve the seven diseases of ageing.

See the NMN factsheet for further information.